Vani Rani, is a story about two sisters, Vani and Rani, who are poles apart in nature. They are married to brothers of the same family and stand by each other.

Siddharth, a hotelier, takes up the responsibility of repairing the relationship between his independent wife, Roshni, and his enterprising mother-in-law, Durga Devi.

Gendas devotion to Maharaj Agrasen is tested when circumstances compel her to challenge her father-in-law Kundan Agarwals patriarchal notions by taking over the responsibility of his beloved shop.

Amruta is a romantic who believes in the bond of love and marriage, while Virat bears the scars of a broken relationship. Will this contrasting duo fall in love against all odds?